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    Our Core Businesses

    Building Blocks

    Key Facts of PharmaBlock Building Blocks

    80,000+ building blocks

    16,000+ in stock

    20,000+ delivered within 2 weeks

    1,000+ SAR/SPR tool kits

    18 core series featuring industry leadership

    60+ chemical series, covering all commenly-used structures in R&D of small molecule drugs 

    Why PharmaBlock

    Novelty & Diversity

    Novel building blocks designed by medicinal chemists upon weekly monitoring on recent research and patents

    Price Advantage

    Keep optimizing cost-effective synthetic route

    Sustainable Supply

    Process developed in advance for scale-up

    Fast Delivery of Custom Synthesis

    Based on profound knowledge and experience in synthesizing core series

    Featured Product Series

    Cyclopropane Series

    Pyrazole & Other Five-Membered Aromatics

    Four-membered Aliphatic Ring Series

    Pyridine, Pyrimidine & Other Six-Membered Aromatics

    Five-membered Aliphatic Ring Series

    Indole, Azaindole & Deazapurine Series

    Six-membered Aliphatic Ring Series

    Other 5,6-Fused Aromatic Series

    Bridged, Spiro & Fused Series

    Quinoline & Other 6,6-Fused Aromatic Series

    Other Series

    No.1 Supplier of 18 Core Series


    Subscribe to PharmaBlock Biweekly Promotional Flyer

    Process Research & Development

    Process R&D Services

    Process route establishment

    Process optimization

    RSM justification studies

    Analytical method development

    Regulatory filing document preparation

    Bulk-scale production of GMP/non-GMP intermediates & RSMs

    GLP synthesis for pre-clinical studies

    Stability studies

    Enabling Technologies

    Continuous Flow Technology:Either with fixed bed hydrogenation flow reactor or self-assembled tube reactors, we develop flow process for safe and seamless scale up.

    Biocatalysis: From screening, optimization to multi kg scale up, we have experience with lipase, KRED, amidase, ATA etc.

    Flow Photochemistry:Scaling up of photoreactions is feasible in PharmaBlock with multiple flow photo reactors.

    Fluorination:With large and special equipment to handle fluorination using F2, HF, SF4 etc., we can supply fluorinated material up to metric tons scale.

    Pilot Plant and Manufacturing

    Why PharmaBlock 

    Process developed in advance for core series products

    Get started quickly on process R&D with accumulated knowledge and experience of building blocks

    Ability to tackle challenging chemistry with enabling technologies

    GMP kilo-lab is in planning

    GMP compliance

    Seamless technology transfer from lab to pilot plant to manufacturing

    EHS compliance, QUALITY assurance, IP protection

    Manufacturing Sites

    Flexible, multi-purpose plants compliant with cGMP and high EHS standards

    Able to practice a wide range of chemistry synthesis and enabling technologies

    Assets to support preclinical, phase I-III, and commercial-scale need

    Seamless process transfer

    Audited by a number of global pharmaceutical companies.

    Shangyu Site

    1,436,000 sq ft

    86 reactors from 300-6300L

    Pilot and commercial production of non-GMP/GMP intermediates & APIs (in planning)

    Diai Site

    807,000 sq ft

    30 reactors from 200-3000L

    Pilot and commercial production of intermediates

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